Health assessment of sports and weight loss products containing synephrine and caffeine

Synephrine, Octopamine and Caffeine Health Risk Assessment (HRA) Report

Issue Assessment of the potential risks to health from natural health products containing synephrine and/or octopamine in combination with caffeine. various products not licensed for sale in Canada Type of Product Natural Health Products Common Name (if any) various Medicinal/Active Ingredient(s) Synephrine and/or Octopamine and Caffeine Dosage Form(s) various Strength(s) various Route of Admin...

A Review of the Human Clinical Studies Involving Citrus aurantium (Bitter Orange) Extract and its Primary Protoalkaloid p-Synephrine

This review summarizes the published as well as unpublished human studies involving Citrus aurantium (bitter orange) extract and its primary protoalkaloid p-synephrine, providing information and an assessment of the safety and efficacy of these widely used products. The results of over 20 studies involving a total of approximately 360 subjects that consumed p-synephrine alone or in combination ...

Review of the Safety Data Available on p-Synephrine, Caffeine, and p-Synephrine- Caffeine Containing Combination Products

Dietary Supplements for Improving Body Composition and Reducing Body Weight: Where Is the Evidence?

Weight-loss supplements typically fall into 1 of 4 categories depending on their hypothesized mechanism of action: products that block the absorption of fat or carbohydrate, stimulants that increase thermogenesis, products that change metabolism and improve body composition, and products that suppress appetite or give a sense of fullness. Each category is reviewed, and an overview of the curren...

Bitter orange, ephedra, and hydroxycitric acid: issues with the article “Dietary supplements for improving body composition and reducing body weight: where is the evidence?”.

Weight-loss supplements typically fall into 1 of 4 categories depending on their hypothesized mechanism of action: products that block the absorption of fat or carbohydrate, stimulants that increase thermogenesis, products that change metabolism and improve body composition, and products that suppress appetite or give a sense of fullness. Each category is reviewed, and an overview of the curren...